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Downstreamprocessing

Wesselingh
ISBN/EAN
9789040712982
Druk
4

Downstream Processing

Dit boekje behandelt het lastige stap van de biotechnologie naar het maken van een produkt. De eigenschappen van deeltjes en stoffen in een fermentatie-vloeistof zijn zo onzeker, dat een ontwerp van een opwerkingsproces niet alleen vanuit de theorie opgezet kan worden. De stappen moeten ook doorgemeten worden.

Inhoud:

Voorwoord

1 Inleiding

2 Celdisruptie / Indeling van methoden / De homogenisator

3 Klaren / Bezinken / Centrifugeren / Filtratie

4 Concentreren / Indampen / Precipitatie / Ultrafiltratie / Uitspoelen

5 Zuiveren / Hulpfasen / Kringlopen / Extractie / Kristallisatie / Antwoorden

6 ZeerZuiveren / Sorptie-processen / Pieken en banden / Gelfiltratie / Ionenwisseling / Affiniteitsadsorptie

7 Schakelen / Een compleet proces / Hoe kan het beter? / Conclusie

8 Literatuur

Symbolen

http://www.vssd.nl/hlf/d003.htm

Uitverkocht


Biotechnology, downstream

Wesselingh, Hans
ISBN/EAN
9789065623959
Druk
2

Content Separating and purifying the desired product is an important part of any bio-project. This processing 'downstream' from the fermenter is both difficult and expensive. Our book intro-duces all the common techniques, starting in the lab and ending in the plant. We have written it for undergraduates in process engineering (biotechnological, mechanical or chemical) and graduate microbiologists doing a minor on the technology that is required to scale up their experiments to a commercial scale. The text is also suitable for courses in industry. The Authors J.A. (Hans) Wesselingh studied engineering physics and worked for the Shell Group for many years. His last job there was as leader of a group developing large scale reactors and separation equipment for oil, gas, chemicals and biotechnology. He later worked as professor on separation processes and product development at Delft University of Technology, the University of Groningen and the Technical University of Denmark. He has been a consultant to many Dutch process industries. John Krijgsman is a mechanical engineer by education and a biochemical engineer by experience. He has worked in the food industry and for many years with the Dutch biotechnology company Gist-Brocades (now part of DSM). He has been a major contributor to large biotechnological projects. John has taught downstream processing to students at the Delft and Eindhoven Universities of Technology. He is owner of Biogonaal, a consultancy for food and biotechnology.

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